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行为诱发的海马θ波:一种胆碱能反应。

Behaviorally evoked hippocampal theta waves: a cholinergic response.

作者信息

Teitelbaum H, Lee J F, Johannessen J N

出版信息

Science. 1975 Jun 13;188(4193):1114-6. doi: 10.1126/science.175440.

DOI:10.1126/science.175440
PMID:175440
Abstract

Forced running in a treadmill results in the instantaneous appearance of a synchronous electroencephalographic pattern in the dorsal hippocampus of the rat. A similar bioelectric response in the absence of movement is induced by physostigmine. Both responses are blocked with scopolamine. Lesions of the medial septal nucleus abolish hippocampal theta waves induced by forced running or physostigmine.

摘要

在跑步机上强迫大鼠奔跑会导致其背侧海马体瞬间出现同步脑电图模式。在没有运动的情况下,毒扁豆碱会诱发类似的生物电反应。这两种反应都可被东莨菪碱阻断。内侧隔核损伤会消除由强迫奔跑或毒扁豆碱诱发的海马体θ波。

相似文献

1
Behaviorally evoked hippocampal theta waves: a cholinergic response.行为诱发的海马θ波:一种胆碱能反应。
Science. 1975 Jun 13;188(4193):1114-6. doi: 10.1126/science.175440.
2
Acetylcholine, theta-rhythm and activity of hippocampal neurons in the rabbit--III. Cortical input.乙酰胆碱、θ节律与家兔海马神经元活动——III. 皮质输入
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Electrophysiological and pharmacological characteristics of facilitation of hippocampal population spikes by stimulation of the medial septum.刺激内侧隔区对海马群体锋电位的易化作用的电生理和药理学特性
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Cholinomimetics induce theta rhythm and reduce hippocampal pyramidal cell excitability.拟胆碱药可诱导θ节律并降低海马锥体细胞兴奋性。
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Acetylcholine, theta-rhythm and activity of hippocampal neurons in the rabbit--II. Septal input.乙酰胆碱、θ节律与家兔海马神经元活动——II. 隔区输入
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To the question of two activating mechanisms: cortical EEG desynchronization and hippocampal "theta" rhythm.关于两种激活机制的问题:皮层脑电图去同步化和海马体“θ”节律。
Act Nerv Super (Praha). 1978 Feb;20(1):22-5.
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Age (Dordr). 2010 Sep;32(3):297-308. doi: 10.1007/s11357-010-9143-y. Epub 2010 Apr 22.
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Effect of voluntary running on adult hippocampal neurogenesis in cholinergic lesioned mice.自愿运动对胆碱能损伤小鼠成年海马神经发生的影响。
BMC Neurosci. 2009 Jun 5;10:57. doi: 10.1186/1471-2202-10-57.
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Persistent hyperdopaminergia decreases the peak frequency of hippocampal theta oscillations during quiet waking and REM sleep.持续性多巴胺能亢进会降低安静觉醒和快速眼动睡眠期间海马θ振荡的峰值频率。
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