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异常子宫出血的现代管理:左炔诺孕酮宫内节育系统

Modern management of abnormal uterine bleeding: the levonorgestrel intra-uterine system.

作者信息

Mansour Diana

机构信息

Graingerville Clinic, Newcastle General Hospital, Newcastle upon Tyne, UK.

出版信息

Best Pract Res Clin Obstet Gynaecol. 2007 Dec;21(6):1007-21. doi: 10.1016/j.bpobgyn.2007.03.023. Epub 2007 Jun 1.

DOI:10.1016/j.bpobgyn.2007.03.023
PMID:17544330
Abstract

Since its launch, more than 9 million women worldwide have used the levonorgestrel intra-uterine system (IUS) for contraception, as a treatment for heavy menstrual bleeding and as the progestogen component of hormone-replacement therapy. For women in their reproductive years, the IUS has become one of the most acceptable medical treatments for menorrhagia, reducing referrals to specialists and decreasing the need for operative gynaecological surgery. This article will outline the development of the IUS, highlighting the most important recent areas of research covering its use to control menstrual blood loss and pain.

摘要

自左炔诺孕酮宫内节育系统(IUS)推出以来,全球已有超过900万女性将其用于避孕、治疗月经过多以及作为激素替代疗法的孕激素成分。对于处于生育年龄的女性来说,IUS已成为治疗月经过多最可接受的医学疗法之一,减少了转诊至专科医生的情况,并降低了妇科手术的必要性。本文将概述IUS的发展历程,重点介绍其在控制月经失血和疼痛方面应用的近期最重要研究领域。

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1
Modern management of abnormal uterine bleeding: the levonorgestrel intra-uterine system.异常子宫出血的现代管理:左炔诺孕酮宫内节育系统
Best Pract Res Clin Obstet Gynaecol. 2007 Dec;21(6):1007-21. doi: 10.1016/j.bpobgyn.2007.03.023. Epub 2007 Jun 1.
2
Levonorgestrel-releasing intrauterine system: uses and controversies.左炔诺孕酮宫内节育系统:用途与争议
Expert Rev Med Devices. 2008 Jul;5(4):437-45. doi: 10.1586/17434440.5.4.437.
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Treatment of menorrhagia with an LNG-IUS.左炔诺孕酮宫内节育系统治疗月经过多
Contraception. 2007 Jun;75(6 Suppl):S118-22. doi: 10.1016/j.contraception.2007.01.008. Epub 2007 Mar 29.
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The levonorgestrel intrauterine system: the benefits of reduced bleeding.左炔诺孕酮宫内节育系统:减少出血的益处。
Eur J Contracept Reprod Health Care. 2001 Jan;6 Suppl 1:27-32.
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Non-contraceptive uses of levonorgestrel-releasing hormone system (LNG-IUS)--a systematic enquiry and overview.左炔诺孕酮释放激素系统(LNG-IUS)的非避孕用途——一项系统的调查与综述
Eur J Obstet Gynecol Reprod Biol. 2006 Mar 1;125(1):9-28. doi: 10.1016/j.ejogrb.2005.10.029. Epub 2005 Dec 1.
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Levonorgestrel intrauterine system: bleeding disorders and anticoagulant therapy.左炔诺孕酮宫内节育系统:出血性疾病与抗凝治疗
Contraception. 2007 Jun;75(6 Suppl):S123-9. doi: 10.1016/j.contraception.2007.01.005. Epub 2007 Mar 23.
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A randomised trial comparing the levonorgestrel intrauterine system and thermal balloon ablation for heavy menstrual bleeding.一项比较左炔诺孕酮宫内节育系统和热球囊消融术治疗月经过多的随机试验。
BJOG. 2006 Mar;113(3):257-63. doi: 10.1111/j.1471-0528.2006.00863.x.
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Randomised comparative trial of the levonorgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment charts.左炔诺孕酮宫内节育系统与甲芬那酸治疗特发性月经过多的随机对照试验:使用总月经液流失、月经失血和图像失血评估图的多分析
BJOG. 2005 Aug;112(8):1121-5. doi: 10.1111/j.1471-0528.2005.00642.x.
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The effectiveness of a levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of endometrial hyperplasia--a long-term follow-up study.左炔诺孕酮宫内节育系统(LNG-IUS)治疗子宫内膜增生的有效性——一项长期随访研究。
Eur J Obstet Gynecol Reprod Biol. 2008 Aug;139(2):169-75. doi: 10.1016/j.ejogrb.2008.02.022. Epub 2008 Apr 28.
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Progestin-releasing intrauterine systems and leiomyoma.释放孕激素的宫内节育系统与平滑肌瘤
Contraception. 2007 Jun;75(6 Suppl):S130-3. doi: 10.1016/j.contraception.2007.01.012. Epub 2007 Mar 9.

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