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直线加速器放射外科和放射治疗听神经瘤

LINAC radiosurgery and radiotherapy treatment of acoustic neuromas.

作者信息

Likhterov Ilya, Allbright Robert M, Selesnick Samuel H

机构信息

Weill Cornell Medical College, 1305 York Avenue; 5th floor, New York, NY 10021, USA.

出版信息

Otolaryngol Clin North Am. 2007 Jun;40(3):541-70, ix. doi: 10.1016/j.otc.2007.03.005.

Abstract

This article provides an introduction to radiation therapy as it applies to intracranial tumors. It also provides a review of the natural growth progression of acoustic neuromas and accuracy of tumor size determination. Literature on the use of linear accelerator stereotactic radiosurgery and fractionated radiotherapy in acoustic neuroma management is reviewed and summarized. Specifically, the rates of reported tumor control, hearing preservation, facial and trigeminal nerve complications, and hydrocephalus are analyzed. Although the complication rates associated with linear accelerator therapy are relatively low, hearing preservation is poor and acoustic neuroma control is variable.

摘要

本文介绍了适用于颅内肿瘤的放射治疗。它还回顾了听神经瘤的自然生长进程以及肿瘤大小测定的准确性。对在听神经瘤治疗中使用直线加速器立体定向放射外科和分次放射治疗的文献进行了综述和总结。具体分析了报告的肿瘤控制率、听力保留率、面部和三叉神经并发症以及脑积水情况。尽管与直线加速器治疗相关的并发症发生率相对较低,但听力保留情况较差,听神经瘤的控制效果也存在差异。

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