Hilgers G, Gargioni E, Grosswendt B, Shchemelinin S
Physikalisch-Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig, Germany.
Radiat Prot Dosimetry. 2007;126(1-4):467-70. doi: 10.1093/rpd/ncm094. Epub 2007 Jun 1.
The frequency distribution of clustered ionizations produced by a proton beam was measured in a nanodosimetric volume of the size of a DNA segment by means of an ion-counting nanodosimeter in the energy range from 0.4 to 3.5 MeV. In order to meet the needs of the ion-counting nanodosimeter, the accelerator's primary beam was reduced in intensity by means of Rutherford scattering. The comparison between experimental results and Monte Carlo simulations show a good agreement in the energy dependence of the mean cluster size, while the experimental cluster size distributions show a higher amount of large ionization clusters compared with those obtained with the simulations.
利用离子计数纳米剂量仪,在0.4至3.5兆电子伏特的能量范围内,在DNA片段大小的纳米剂量体积中测量了质子束产生的簇状电离的频率分布。为了满足离子计数纳米剂量仪的需求,通过卢瑟福散射降低了加速器初级束的强度。实验结果与蒙特卡罗模拟之间的比较表明,在平均簇尺寸的能量依赖性方面有很好的一致性,而实验得到的簇尺寸分布显示,与模拟结果相比,大电离簇的数量更多。