40岁及以上女性宫颈细胞学检查中发现的子宫内膜细胞：适当子宫内膜评估的标准
Endometrial cells identified in cervical cytology in women > or = 40 years of age: criteria for appropriate endometrial evaluation.
作者信息
Beal Heather N, Stone Jason, Beckmann Michael J, McAsey Mary E
机构信息
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL.
出版信息
Am J Obstet Gynecol. 2007 Jun;196(6):568.e1-5; discussion 568.e5-6. doi: 10.1016/j.ajog.2007.01.040.
OBJECTIVE
No consensus exists regarding evaluation of asymptomatic premenopausal women with benign endometrial cells (BECs) identified on cervical cytology. We determined the frequency of uterine pathology in asymptomatic women, > or = 40 years of age, positive for BECs on cervical cytology.
STUDY DESIGN
Cervical cytopathology records from a Midwestern US teaching hospital from April 2002 through December 2005 were reviewed and cases with BECs identified. Patient age, symptomatology, and endometrial sampling results were obtained.
RESULTS
Of 194,717 records examined, 1784 (0.9%) of women > or = 40 years had BECs present and 440 had follow-up endometrial pathology. There were 4 cases of complex hyperplasia with atypia, 2 from patients < or = 50 years, 1 was asymptomatic; 4 cases of adenocarcinoma were identified, all from women > 50 years.
CONCLUSION
To date, the present study is among the largest follow-up studies of women with BECs on cervical cytology. Follow-up endometrial sampling may not be indicated in asymptomatic patients < or = 50 years.
目的
对于宫颈细胞学检查发现有良性子宫内膜细胞（BECs）的无症状绝经前女性，目前尚无关于评估的共识。我们确定了宫颈细胞学检查BECs呈阳性、年龄≥40岁的无症状女性子宫病变的发生率。
研究设计
回顾了美国中西部一家教学医院2002年4月至2005年12月的宫颈细胞病理学记录，并确定了有BECs的病例。获取了患者年龄、症状和子宫内膜取样结果。
结果
在检查的194,717份记录中，1784名（0.9%）年龄≥40岁的女性有BECs，440名进行了后续子宫内膜病理学检查。有4例复杂性不典型增生，其中2例来自年龄≤50岁的患者，1例无症状；发现4例腺癌，均来自年龄>50岁的女性。
结论
迄今为止，本研究是对宫颈细胞学检查有BECs的女性进行的最大规模随访研究之一。对于年龄≤50岁的无症状患者，可能无需进行后续子宫内膜取样。
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