Mtiraoui N, Zammiti W, Fekih M, Hider S, Almawi W Y, Mahjoub T
Research Unit of Haematological and Autoimmune Diseases, Faculty of Pharmacy, University of Monastir, Monastir.
Fertil Steril. 2007 Nov;88(5):1458-61. doi: 10.1016/j.fertnstert.2007.01.026. Epub 2007 Jun 4.
The prevalence of lupus anticoagulant (LAC), anticardiolipin (ACA), anti-beta(2) glycoprotein I (beta(2)GPI), and antiannexin V antibodies were determined in 200 recurrent spontaneous abortion (RSA) patients and 200 age-matched control women. ACA IgG was associated with early, while antiannexin V IgG and LAC were associated with late, and ACA IgG, antiannexin V IgG, and LAC were associated with combined early + late RSA, thereby recommending inclusion of their screening in RSA workout.
在200例复发性自然流产（RSA）患者和200例年龄匹配的对照女性中，检测了狼疮抗凝物（LAC）、抗心磷脂（ACA）、抗β2糖蛋白I（β2GPI）和抗膜联蛋白V抗体的患病率。ACA IgG与早期RSA相关，而抗膜联蛋白V IgG和LAC与晚期RSA相关，ACA IgG、抗膜联蛋白V IgG和LAC与早期+晚期RSA合并相关，因此建议在RSA检查中纳入对它们的筛查。
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