Acai P, Polakovic M
Department of Chemical and Biochemical Engineering, Institute of Chemical and Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovak Republic.
J Biotechnol. 2007 Oct 31;132(2):149-55. doi: 10.1016/j.jbiotec.2007.04.008. Epub 2007 May 4.
The design of a large-scale bioreactor for the production of bacterial biomass adapted to the biodegradation of volatile organic compounds was carried out. The bioreactor model used integrated the microbial kinetics and fluid dynamics described by the compartment model approach. The process conditions and kinetic parameters were adopted from the laboratory experimental study of (León, E., Seignez, C., Adler, N., Péringer, P., 1999. Growth inhibition of biomass adapted to the degradation of toluene and xylenes in mixture in a batch reactor with substrates supplied by pulses. Biodegradation 10, 245-250). The performance of the pulsed-batch stirred bioreactor under surface aeration conditions was simulated for different mixing configurations and conditions such as the impeller diameter, number of impellers, stirring speed, and oxygen pressure. The simulations were used for the cost analysis which resulted in the optimal design of the bioreactor.
开展了用于生产适应挥发性有机化合物生物降解的细菌生物质的大型生物反应器的设计。所使用的生物反应器模型整合了由隔室模型方法描述的微生物动力学和流体动力学。工艺条件和动力学参数取自（莱昂，E.，塞涅兹，C.，阿德勒，N.，佩林格，P.，1999年。在间歇式反应器中通过脉冲供应底物，适应甲苯和二甲苯混合物降解的生物质的生长抑制。生物降解10，245 - 250）的实验室实验研究。针对不同的混合配置和条件，如叶轮直径、叶轮数量、搅拌速度和氧气压力，模拟了表面曝气条件下脉冲间歇搅拌生物反应器的性能。这些模拟用于成本分析，从而得出生物反应器的优化设计。
