Wong K S, Huang Y N, Yang H B, Gao S, Li H, Liu J Y, Liu Y, Tang A
Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.
Neurology. 2007 Jun 5;68(23):2031-4. doi: 10.1212/01.wnl.0000264426.63544.ee.
We studied 590 asymptomatic villagers aged > or =40 years in Liangbei County in central rural China and found 41 subjects (prevalence 6.9%) with intracranial atherosclerosis. In a multivariate analysis, the significant risk factors for intracranial stenosis were hypertension (OR 2.53; 95% CI 1.12 to 5.72), glycosuria (OR 3; 1.19 to 7.97), heart disease (OR 4; 1.39 to 11.6), and family history of stroke (OR 5.2; 1.38 to 20). Intracranial atherosclerosis is not uncommon among asymptomatic Chinese subjects.
我们对中国中部农村梁北县590名年龄≥40岁的无症状村民进行了研究,发现41名受试者(患病率6.9%)存在颅内动脉粥样硬化。多因素分析显示,颅内狭窄的显著危险因素为高血压(比值比2.53;95%置信区间1.12至5.72)、糖尿(比值比3;1.19至7.97)、心脏病(比值比4;1.39至11.6)以及卒中家族史(比值比5.2;1.38至20)。颅内动脉粥样硬化在无症状中国受试者中并不罕见。