Godeau P, Guillevin L, de Saxce H, Le Porrier M
Sem Hop. 1975 Oct 9;51(40):2401-5.
The authors report a case of Hodgkin's disease at the subdiaphragmatic II B b stage with cell type III, revealed by thrombopenic purpura. Laparotomy and splenectomy confirmed the invasion of the spleen whereas there was no clinical splenomegaly and splenic radio-isotope scan was normal. The course is at present favourable, the purpura has been treated by corticotherapy then splenectomy, and the disease has been brought under control by classical treatment (cobalt radiotherapy and chemotherapy). The authors then discuss eight other cases in the world literature. Splenectomy is of dual interest for the assessment of Hodgkin's disease, on the one hand, and for the treatment of thrombopenic purpura on the other hand.
作者报告了1例因血小板减少性紫癜而发现的膈下II B b期III型细胞霍奇金病。剖腹术和脾切除术证实脾脏受到侵犯，而临床上无脾肿大，脾脏放射性同位素扫描正常。目前病情好转，紫癜先采用皮质激素疗法治疗，后行脾切除术，疾病已通过经典治疗（钴放疗和化疗）得到控制。作者随后讨论了世界文献中的其他8例病例。脾切除术一方面对霍奇金病的评估有双重意义，另一方面对血小板减少性紫癜的治疗也有意义。
