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[自体骨髓单个核细胞植入治疗股骨头坏死]

[Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow mononuclear cells].

作者信息

Yasunaga Yuji, Terayama Hiroshi, Yamasaki Takuma, Ishikawa Masakazu, Ochi Mitsuo

机构信息

Hiroshima University, Graduate School of Biomedical Sciences, Department of Artificial joints & Biomaterials.

出版信息

Clin Calcium. 2007 Jun;17(6):910-5.

Abstract

Idiopathic osteonecrosis of the femoral head commonly develops during adolescence and in the prime of adulthood. In Japan, joint-preserving procedures such as transtrochanteric rotational osteotomy, femoral varus osteotomy and vascularized bone grafting are often the surgical treatments of choice. However, the results of these procedures are not necessarily satisfactory. These procedures force patients to endure longer waits for their entire treatment. In addition, it is often difficult for surgeons to choose the appropriate treatment, especially in patients who have bilateral extensive osteonecrosis. We reported transplantation of bone marrow mononuclear cells for osteonecrosis of the femoral head and short-term results.

摘要

股骨头特发性骨坏死通常在青春期和成年盛期发病。在日本,诸如经转子旋转截骨术、股骨内翻截骨术和带血管蒂骨移植术等保关节手术常常是首选的外科治疗方法。然而,这些手术的效果未必令人满意。这些手术使患者在整个治疗过程中需要等待更长时间。此外,外科医生通常很难选择合适的治疗方法,尤其是对于双侧广泛骨坏死的患者。我们报道了骨髓单个核细胞移植治疗股骨头骨坏死及其短期疗效。

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