Iwamuro Masaya, Kubota Junichi, Saito Shunsuke, Goubaru Motohiro, Ohta Takeyuki, Ogata Masatoshi, Takuma Yoshitaka, Tanaka Shouichi, Makino Yasuhiro, Murakami Ichiro
Department of Internal Medicine, National Hospital Organization Iwakuni Clinical Center.
Nihon Shokakibyo Gakkai Zasshi. 2007 Jun;104(6):829-36.
A 30-year-old woman was referred to us because of hypoglycemic attack. The tumor on the pancreatic body of 22 mm size was revealed by close inspection, and was diagnosed as insulinoma. Surgical resection was performed, but curative resection was impossible because the component of adenocarcinoma infiltrating into surrounding tissue coexisted with insulinoma. Postoperatively, we make a diagnosis of combined tumor of the pancreas, i.e. mixed duct-islet cell carcinoma. In this paper, we discuss this rare disorder and summarize 33 cases reported in the Japanese literature.
一名30岁女性因低血糖发作前来我院就诊。经仔细检查发现胰体部有一个22毫米大小的肿瘤,诊断为胰岛素瘤。进行了手术切除,但由于腺癌成分浸润周围组织与胰岛素瘤并存,无法进行根治性切除。术后,我们诊断为胰腺混合性肿瘤,即混合性导管-胰岛细胞癌。在本文中,我们讨论了这种罕见疾病,并总结了日本文献报道的33例病例。