Jonville A P, Lionnet C, Swar A, Dutertre J P, Barbier P, Autret E, Berger C
Service de Pharmacologie Clinique, CHRU Bretonneau, Tours.
Therapie. 1991 Sep-Oct;46(5):379-82.
To evaluate drug utilization during the last 15 days of pregnancy, one hundred six women were interviewed post-delivery in the CHU Bretonneau in Tours. Eighty-three percent received at least one drug during the 15 days preceding delivery and 27% more than 3 different drugs. Treatments for venous disorders (31% of patients), iron (31%), analgesics (25%), antacids (11%), magnesium (11%) and laxatives (11%) were most frequently used. In 92% of cases the drug was prescribed. Five women received a drug with potential risk for the neonate. However only one infant developed and adverse effect, possibly due to benzodiazepine (hypotonia).
为评估孕期最后15天的药物使用情况，在图尔的布雷托诺医院对106名产后妇女进行了访谈。83%的妇女在分娩前15天内至少使用了一种药物，27%的妇女使用了3种以上不同药物。最常使用的治疗药物为：治疗静脉疾病的药物（占患者的31%）、铁剂（31%）、镇痛药（25%）、抗酸剂（11%）、镁剂（11%）和泻药（11%）。92%的药物是由医生开出处方的。5名妇女使用了对新生儿有潜在风险的药物。然而，只有一名婴儿出现了不良反应，可能是由于苯二氮䓬类药物（肌张力减退）。
