Boldyreva Galina N, Zhavoronkova Ludmila A, Sharova Elena V, Dobronravova Irina S
Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences, Moscow.
Span J Psychol. 2007 May;10(1):167-77. doi: 10.1017/s1138741600006430.
The authors summarized EEG findings and defined the nature of the intercentral EEG relationships in different functional states in healthy subjects and patients with organic cerebral pathology, based on a coherence analysis. Similar EEG characteristics in healthy individuals were identified: an anterior-posterior gradient of average coherence levels, the type of cortical-subcortical relationships in anterior cerebral structures. Right- and left-handed individuals showed frequent and regional differences in EEG coherence, which mainly reflected specificity of intracortical relationships. Development and regression of pathology in right-and left-handed individuals with organic brain lesions were thought to be caused by these differences. Lesions of regulatory structures (diencephalic, brain stem and limbic structures) provoked a more diffused kind of changes of intercentral relationships, in contrast to cortical pathology. These changes tended to reciprocate. The dynamic nature of intercentral relationships and their interhemispheric differences was revealed when changing functional states of the brain (increase and decrease of functional level) in healthy individuals and patients with organic cerebral pathology in the process of conscious and psychic activity restoration. Changing activity predominance of certain regulatory structures was considered one of the most important factors determining the dynamic nature of EEG coherence.
作者基于相干分析总结了脑电图（EEG）的研究结果，并确定了健康受试者和患有器质性脑病变患者在不同功能状态下中央间EEG关系的性质。在健康个体中发现了类似的EEG特征：平均相干水平的前后梯度，大脑前部结构中皮质 - 皮质下关系的类型。右利手和左利手个体在EEG相干性方面表现出频繁且局部的差异，这主要反映了皮质内关系的特异性。患有器质性脑损伤的右利手和左利手个体的病理发展和消退被认为是由这些差异引起的。与皮质病变相比，调节结构（间脑、脑干和边缘系统结构）的损伤引发了一种更为弥漫的中央间关系变化。这些变化往往是相互的。在健康个体和患有器质性脑病变的患者在意识和心理活动恢复过程中，当大脑功能状态发生变化（功能水平的增加和降低）时，揭示了中央间关系的动态性质及其半球间差异。某些调节结构活动优势的变化被认为是决定EEG相干性动态性质的最重要因素之一。
