Marsh Graham P, Parsons Philip J, McCarthy Clive, Corniquet Xavier G
Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
Org Lett. 2007 Jul 5;9(14):2613-6. doi: 10.1021/ol070557k. Epub 2007 Jun 6.
A synthesis of highly functionalized nitroalkenes is reported that utilizes a cross metathesis (CM) reaction between simple aliphatic nitro compounds and a range of substituted alkenes. This chemistry offers a simple and attractive route to nitroalkenes that would otherwise be difficult to prepare, and that have a very useful application as precursors to a variety of heterocyclic entities.
报道了一种高官能化硝基烯烃的合成方法，该方法利用简单脂肪族硝基化合物与一系列取代烯烃之间的交叉复分解（CM）反应。这种化学方法为硝基烯烃提供了一条简单且有吸引力的合成途径，否则这些硝基烯烃很难制备，并且它们作为多种杂环化合物前体具有非常有用的应用。
