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假冒或不合格抗菌药物:科学证据综述

Counterfeit or substandard antimicrobial drugs: a review of the scientific evidence.

作者信息

Kelesidis Theodore, Kelesidis Iosif, Rafailidis Petros I, Falagas Matthew E

机构信息

Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece.

出版信息

J Antimicrob Chemother. 2007 Aug;60(2):214-36. doi: 10.1093/jac/dkm109. Epub 2007 Jun 5.

DOI:10.1093/jac/dkm109
PMID:17550892
Abstract

There is growing universal concern regarding counterfeit medications. In particular, counterfeit antimicrobial drugs are a threat to public health with many devastating consequences for patients; increased mortality and morbidity and emergence of drug resistance. In addition, physicians treating these patients lose their confidence in the medications used and report high levels of bacterial resistance. The problem with fake and suboptimal medications got worse with the advent of the World Wide Web; a significant proportion of medications that are sold through Internet pharmacies is counterfeit. Various initiatives of the WHO (the International Medical Products Anti-Counterfeiting Taskforce) are hopefully going to tackle this very important public health issue. In this article, we review the available evidence in peer-reviewed articles and World Wide Web information resources regarding the issue of counterfeit antimicrobials.

摘要

假冒药品日益引起全球关注。尤其是假冒抗菌药物对公众健康构成威胁,给患者带来诸多严重后果,如死亡率和发病率上升以及耐药性的出现。此外,治疗这些患者的医生对所用药物失去信心,并报告了高水平的细菌耐药性。随着万维网的出现,假冒和质量欠佳的药品问题变得更加严重;通过网上药店销售的药品中有很大一部分是假冒的。世卫组织(国际医疗产品打假专题小组)的各项举措有望解决这一非常重要的公共卫生问题。在本文中,我们回顾了同行评审文章和万维网信息资源中关于假冒抗菌药物问题的现有证据。

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