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立陶宛的原发性肾小球疾病:肾活检病例回顾性分析(2000 - 2006年)

[Primary glomerulopathies in Lithuania: a retrospective analysis of renal biopsy cases (2000-2006)].

作者信息

Beitnaraite Sandra, Kovaliūnas Edvardas, Laurinavicius Arvydas

机构信息

1Faculty of Medicine, Vilnius University, Lithuania.

出版信息

Medicina (Kaunas). 2007;43 Suppl 1:6-10.

Abstract

A retrospective study of 1363 native kidney biopsies, performed at Lithuanian nephrology units and investigated at the National Center of Pathology during the period of 2000-2006, was carried out. Inflammatory glomerulopathies constituted 63.6% of all primary glomerulopathies (834 cases); IgA nephropathy was the most frequent disease (35.0%). The incidence of membranoproliferative glomerulonephritis decreased from 22.6% reported in Lithuania previously (1995-1999) to 16.7% in this study; however, it was still higher compared to most European countries. Extracapillary proliferative glomerulonephritis and diffuse endocapillary proliferative glomerulonephritis accounted for 9.1% and 4.4%, respectively. Noninflammatory glomerulopathies were relatively rare: focal and segmental glomerulosclerosis made up 14.8%; minimal change disease, 9.7%; membranous nephropathy, 7.4%. However, their incidence increased compared to the previously reported in 1995-1999 (9.5%, 5.8%, and 4.3%, respectively). It can be concluded that inflammatory glomerulopathies were predominant in Lithuania in 2000-2006; however, these glomerulopathies were less prominent as compared to the previously reported data in 1995-1999.

摘要

对2000年至2006年期间在立陶宛肾脏病科进行并在国家病理中心研究的1363例自体肾活检进行了回顾性研究。炎症性肾小球病占所有原发性肾小球病的63.6%(834例);IgA肾病是最常见的疾病(35.0%)。膜增生性肾小球肾炎的发病率从立陶宛先前报告的22.6%(1995 - 1999年)降至本研究中的16.7%;然而,与大多数欧洲国家相比,其发病率仍然较高。毛细血管外增生性肾小球肾炎和弥漫性毛细血管内增生性肾小球肾炎分别占9.1%和4.4%。非炎症性肾小球病相对少见:局灶节段性肾小球硬化占14.8%;微小病变病占9.7%;膜性肾病占7.4%。然而,与1995 - 1999年先前报告的发病率相比有所增加(分别为9.5%、5.8%和4.3%)。可以得出结论,2000 - 2006年立陶宛炎症性肾小球病占主导地位;然而,与1995 - 1999年先前报告的数据相比,这些肾小球病不那么突出。

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