马其顿共和国经活检证实的原发性肾小球肾炎发病率——长期随访

The incidence of biopsy-proven primary glomerulonephritis in the Republic of Macedonia-long-term follow-up.

作者信息

Polenakovic Momir H, Grcevska Ladislava, Dzikova Sonja

机构信息

Department of Nephrology, Clinical Center, Skopje, Republic of Macedonia.

出版信息

Nephrol Dial Transplant. 2003 Jul;18 Suppl 5:v26-7. doi: 10.1093/ndt/gfg1039.

DOI:10.1093/ndt/gfg1039

PMID:12817063

Abstract

In order to define the type of renal disease, renal biopsy was performed in 1304 patients, aged 14-72 years. Their biopsies were processed for light and immunofluorescence microscopy, and electron microscopy in some cases. The diagnosis of primary glomerular disease was confirmed in 716 patients with the following incidence: minimal change nephrotic syndrome in 52 (7.2%), focal segmental glomerulosclerosis in 72 (9.9%), membranous nephropathy in 97 (13.5%), IgA nephropathy in 85 (11.8%), diffuse mesangial glomerulonephritis (GN) without IgA in 32 (4.4%), focal mesangial GN in 97 (13.5%), membranoproliferative GN in 59 (8.4%), acute GN in 88 (12.3%), crescentic GN in 53 (7.4%) and sclerosing GN in 46 patients (6.4%).

摘要

为明确肾脏疾病的类型，对1304例年龄在14至72岁的患者进行了肾活检。对其活检组织进行了光镜、免疫荧光显微镜检查，部分病例还进行了电镜检查。716例患者确诊为原发性肾小球疾病，其发病率如下：微小病变肾病52例（7.2%），局灶节段性肾小球硬化72例（9.9%），膜性肾病97例（13.5%），IgA肾病85例（11.8%），无IgA的弥漫性系膜增生性肾小球肾炎（GN）32例（4.4%），局灶性系膜增生性GN 97例（13.5%），膜增生性GN 59例（8.4%），急性GN 88例（12.3%），新月体性GN 53例（7.4%），硬化性GN 46例（6.4%）。