Murukeshan V M, Sujatha N
Photonics and Microsciences Laboratory, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Rev Sci Instrum. 2007 May;78(5):053106. doi: 10.1063/1.2737772.
Disease detection in body cavities, such as the detection of abnormal growths in the colon path, has been illustrated here using an image fiber guided catheter based multispeckle modality endoscopic system. An all fiber-optic approach for the illumination and imaging of the inner cavity walls is adopted here. An endoscope probe to carry the illumination fibers as well as the imaging lens-image fiber unit is designed and custom fabricated in order to operate the probe in its various direction sensitive configurations. This is facilitated by the selection of suitable optical elements such as beam combiner and biprism at the probe proximal end. Experimental investigations were carried out using the endoscope system employing phantom model of colon as the test specimen that has normal and abnormal (representing growth) regions and the obtained results indicated the system effectiveness in identifying the abnormal growths at an early stage.
本文展示了利用基于图像光纤引导导管的多散斑模态内窥镜系统在体腔中进行疾病检测，如在结肠路径中检测异常生长物。这里采用全光纤方法对内腔壁进行照明和成像。设计并定制制造了一种内窥镜探头，用于承载照明光纤以及成像透镜-图像光纤单元，以便使探头在其各种方向敏感配置下运行。这通过在探头近端选择合适的光学元件（如光束组合器和双棱镜）来实现。使用以结肠模型为测试样本的内窥镜系统进行了实验研究，该模型具有正常和异常（代表生长）区域，获得的结果表明该系统在早期识别异常生长物方面的有效性。
