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[群马县及其周边地区1985年至1989年期间前列腺癌患者的统计分析]

[Statistical analysis of the prostatic cancer patients detected from 1985 to 1989 in and around Gunma prefecture].

作者信息

Nakata S, Imai K, Uchida T, Yamanaka H, Hashimoto K, Ogura H, Nakano K, Kurita M, Saito Y, Ono Y

机构信息

Department of Urology, Gunma University, School of Medicine.

出版信息

Hinyokika Kiyo. 1991 Oct;37(10):1261-9; discussion 1269-70.

PMID:1755419
Abstract

Prostatic cancer is one of the most common malignant tumors in the field of urology. The number of patients is increasing rapidly and its importance as a mortal disease is gathering attention. In 1985, we organized a registration system for prostatic cancer patients found in and around Gunma prefecture. In this study, we analyzed the clinical characteristics of the 730 patients registered from 1985 to 1989. The results were as follows. Mean age was 74.0 years old and the number of the patients was the greatest in the eighth decade. Voiding disturbance was the most common chief complaint, followed by pollakisuria, gross hematuria and miction pain. Stage and grade distribution were as follows. Stage A 16.2%, B 21.1%, C 17.0%, D 45.7%, well differentiated 27.4%, moderately differentiated 48.2% and poorly differentiated 24.5%, respectively. A statistically significant relationship between stage and grade was observed. Bone was the most common metastatic site. The highest incidence of bone metastasis was in lumbar vertebra, followed by ribs, ilium, thoracic vertebra and ischium. The value of PAP, ALP and ESR tended to be higher in high stage patients, and that of Hb was lower. Fifty two patients were detected by mass screening. Most of these patients were in an early stage. Most of the patients were treated by hormonal therapy. LH-RH agonists constituted 39.2% of the cases given hormonal therapy.

摘要

前列腺癌是泌尿外科领域最常见的恶性肿瘤之一。患者数量正在迅速增加,其作为一种致命疾病的重要性日益受到关注。1985年,我们组织了一个针对群马县及周边地区发现的前列腺癌患者的登记系统。在本研究中,我们分析了1985年至1989年登记的730例患者的临床特征。结果如下。平均年龄为74.0岁,患者数量在八十岁年龄段最多。排尿障碍是最常见的主要症状,其次是尿频、肉眼血尿和排尿疼痛。分期和分级分布如下。A期16.2%,B期21.1%,C期17.0%,D期45.7%,高分化27.4%,中分化48.2%,低分化24.5%。观察到分期和分级之间存在统计学上的显著关系。骨是最常见的转移部位。骨转移的最高发生率在腰椎,其次是肋骨、髂骨、胸椎和坐骨。PAP、ALP和ESR的值在晚期患者中往往较高,而Hb的值较低。52例患者通过大规模筛查被检测出。这些患者大多处于早期。大多数患者接受了激素治疗。促性腺激素释放激素激动剂占接受激素治疗病例的39.2%。

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