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1例戈登分枝杆菌肺部感染未经治疗病情进展

[A case of pulmonary Mycobacterium gordonae infection progressed for no therapy].

作者信息

Konishi Mitsuru, Uno Kenji, Kasahara Kei, Mori Kei, Yoshimoto Eiichiro, Maeda Koichi, Mikasa Keiichi

机构信息

Center for Infectious Diseases, Nara Medical University.

出版信息

Nihon Kokyuki Gakkai Zasshi. 2007 May;45(5):436-40.

Abstract

A 68-year-old woman, who had been healthy until this event, presented with a complaint of productive cough since 2000. She went to a neighboring hospital because of bloody sputum in October 2001. Although chest radiograph showed abnormal findings then, she received only an expectorant and cough remedy. She consulted us complaining of dyspnea on exertion in April 2005. Chest radiograph revealed cavity formation, bronchiectasis and a nodular shadow, and her condition had deteriorated. Microbiologically, acid-fast bacilli were detected three times in the culture of sputum, and Mycobacterium gordonae was identified by the biochemical method. However, this Mycobacterium gordonae could not be identified by the DNA-DNA hybridization method. Our case also probably was considered to be a primary type pulmonary nontuberculous infection because of her clinical course. In addition, we recognized that pulmonary M. gordonae infection also worsens without the therapy.

摘要

一名68岁女性,在此之前身体一直健康,自2000年起出现咳痰症状。2001年10月,她因咯血痰前往附近医院就诊。当时胸部X线片显示有异常表现,但她仅接受了祛痰药和止咳药治疗。2005年4月,她因活动后呼吸困难前来咨询我们。胸部X线片显示有空洞形成、支气管扩张和结节状阴影,病情已经恶化。微生物学检查方面,痰培养中三次检测到抗酸杆菌,通过生化方法鉴定为戈登分枝杆菌。然而,通过DNA - DNA杂交方法未能鉴定出该戈登分枝杆菌。从她的临床病程来看,我们的病例可能也被认为是原发性肺非结核感染。此外,我们认识到肺部戈登分枝杆菌感染在未经治疗的情况下也会恶化。

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