Terashima T, Umeda A, Sakamaki F, Kanazawa M, Kawashiro T
Department of Medicine, School of Medicine, Keio University, Tokyo, Japan.
Kekkaku. 1993 Oct;68(10):653-6.
A 54-year old man with pulmonary disease due to Mycobacterium xenopi is described. He had a history of pulmonary tuberculosis at 8 years of age. He was admitted to our hospital in October 1992, complaining of productive cough and fever. A chest X-ray on October 20 showed an infiltrative shadow with a cavity, although chest X-ray picture on October 2 showed only inactive shadow, in the right upper lobe. Acid-fast organisms were seen in his sputum specimens and M. xenopi was identified by culture. The isolates were confirmed to be M. xenopi by the DNA-DNA hybridization method. He was treated with isoniazid, rifampicin and streptomycin. The fever decreased within a week. After two months of therapy, sputum cultures became negative and chest X-ray findings improved. It was concluded that this is a case of rapidly progressed pulmonary disease caused by M. xenopi in the normal host. This patient's condition responded to antituberculosis drugs.
本文描述了一名54岁因偶发分枝杆菌导致肺部疾病的男性患者。他8岁时曾患肺结核。1992年10月因咳嗽咳痰和发热入院。10月20日胸部X线显示右上叶有浸润性阴影伴空洞形成，而10月2日的胸部X线片仅显示右上叶有陈旧性阴影。痰标本中发现抗酸菌，经培养鉴定为偶发分枝杆菌。通过DNA-DNA杂交法确认分离菌株为偶发分枝杆菌。给予异烟肼、利福平及链霉素治疗。一周内体温下降。治疗两个月后，痰培养转阴，胸部X线表现改善。结论为该病例是正常宿主中由偶发分枝杆菌引起的快速进展性肺部疾病，患者病情对抗结核药物有反应。
