Benca J, Ondrusova A, Huttova M, Rudinsky B, Kisac P, Bauer F
John Paul School of Missiology and Tropical Health, Bratislava, Slovakia.
Neuro Endocrinol Lett. 2007 Jun;28 Suppl 2:32-3.
Enterococcal meningitis is a rare complication of neurosurgical procedure or high technology treatment of children and occurs mainly imunocompromised neonates with very low birth weight, severe prematurity and complicates sometime ventriculoperitoneal shunt insertion or perinatal trauma. E. faecalis caused 10 nosocomial meningitis and all strains were susceptible to vancomycin and chloramphenicol, and in our database 90% also to gentamicin and ampicillin. Mortality in our group of 10 children was 20% what is insignificantly higher than overall mortality in the whole cohort of meningitis within last 15 years in our database (15.1%). Early empiric therapy should include also ampicillin or vancomycin, if enterococcal etiology is suspected.
肠球菌性脑膜炎是儿童神经外科手术或高科技治疗的一种罕见并发症,主要发生在免疫功能低下、极低出生体重、严重早产的新生儿中,有时会并发脑室腹腔分流术插入或围产期创伤。粪肠球菌引起了10例医院获得性脑膜炎,所有菌株对万古霉素和氯霉素敏感,在我们的数据库中,90%的菌株对庆大霉素和氨苄西林也敏感。我们这组10名儿童的死亡率为20%,略高于我们数据库中过去15年整个脑膜炎队列的总体死亡率(15.1%)。如果怀疑是肠球菌病因,早期经验性治疗也应包括氨苄西林或万古霉素。