Ezzie Michael E, Crouser Elliott D
Division of Pulmonary, Critical Care, and Sleep Medicine, The Ohio State University Medical Center, Columbus, OH 43210-1252, USA.
Clin Dermatol. 2007 May-Jun;25(3):259-66. doi: 10.1016/j.clindermatol.2007.03.003.
Sarcoidosis is a systemic granulomatous disease of unknown cause. An infectious etiology of sarcoidosis has long been suspected, but only recently has scientific evidence provided a strong link between infectious agents and sarcoidosis. Moreover, recent advances in our understanding of the relationships between sarcoidosis phenotype and host genetic factors may further illuminate the mechanisms linking infection and sarcoidosis.
结节病是一种病因不明的全身性肉芽肿性疾病。长期以来,人们一直怀疑结节病具有感染性病因,但直到最近,科学证据才证实了感染因子与结节病之间存在紧密联系。此外,我们对结节病表型与宿主遗传因素之间关系的最新认识进展,可能会进一步阐明感染与结节病之间的关联机制。