Gardiner Keith R, Dasari Bobby V M
Royal Victoria Hospital, Grosvenor Road, Belfast, Northern Ireland, UK.
Surg Clin North Am. 2007 Jun;87(3):587-610. doi: 10.1016/j.suc.2007.03.011.
Despite advances in medical treatment, most patients who have Crohn's disease of the small intestine need surgery at some point during the course of their disease. Surgery is currently indicated for intractable disease and complications of the disease (strictures, abscesses, fistulas, hemorrhage). There is increasing interest in nonsurgical and minimal access strategies of dealing with complicated disease, however. These new approaches may enable postponement of surgery to a more favorable time, or conversion of a two-stage procedure involving a stoma to a one-stage resection with anastomosis. A continuing challenge is prevention of disease recurrence postoperatively.
尽管医学治疗取得了进展,但大多数患有小肠克罗恩病的患者在疾病过程中的某个阶段仍需要进行手术。目前,手术适用于难治性疾病以及该疾病的并发症(狭窄、脓肿、瘘管、出血)。然而,人们对处理复杂疾病的非手术和微创策略的兴趣与日俱增。这些新方法可能会使手术推迟到更有利的时机,或者将涉及造口的两阶段手术转变为一期切除吻合术。术后预防疾病复发仍是一个持续的挑战。