胃残端癌与原发性近端胃癌的治疗及预后比较
Treatment and prognosis of gastric stump carcinoma in comparison with primary proximal gastric cancer.
作者信息
Schaefer Nico, Sinning Christoph, Standop Jens, Overhaus Marcus, Hirner Andreas, Wolff Martin
机构信息
Department of Surgery, University of Bonn, Bonn, Germany.
出版信息
Am J Surg. 2007 Jul;194(1):63-7. doi: 10.1016/j.amjsurg.2006.12.037.
BACKGROUND
The intention of this study was to evaluate the outcome of patients with gastric stump cancer (GSC) in comparison with patients treated for primary proximal gastric cancer (PPGC).
METHODS
Nineteen patients with GSC undergoing surgery between January 1989 and August 2005 were compared with 194 PPGC patients treated during the same time period. Various factors such as epidemiologic data, type of treatment, and histopathologic data were evaluated in the analysis.
RESULTS
The overall 5-year disease-specific survival was 42% for resected GSC patients in comparison with 37% for resected PPGC patients. There was no statistically significant difference in the survival rate detected between these 2 groups. On multivariate analysis the infiltration of the gastrojejunal anastomosis by the carcinoma was shown to be a significant predictor for the outcome of patients with GSC.
CONCLUSIONS
In summary, no significant difference in the outcome between GSC and PPGC has been detected.
背景
本研究旨在评估胃残端癌（GSC）患者与原发性近端胃癌（PPGC）患者的治疗结果。
方法
将1989年1月至2005年8月期间接受手术的19例GSC患者与同期治疗的194例PPGC患者进行比较。分析中评估了各种因素，如流行病学数据、治疗类型和组织病理学数据。
结果
切除的GSC患者的5年疾病特异性生存率为42%，而切除的PPGC患者为37%。这两组之间的生存率没有统计学上的显著差异。多因素分析显示，癌组织对胃肠吻合口的浸润是GSC患者预后的重要预测因素。
结论
总之，未发现GSC和PPGC患者的治疗结果有显著差异。
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