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产后发作的重度抑郁症与人格障碍有关。

Postpartum-onset major depression is associated with personality disorders.

作者信息

Akman Cemal, Uguz Faruk, Kaya Nazmiye

机构信息

Department of Psychiatry, Meram Faculty of Medicine, Selcuk University, Meram Konya 42080, Turkey.

出版信息

Compr Psychiatry. 2007 Jul-Aug;48(4):343-7. doi: 10.1016/j.comppsych.2007.03.005. Epub 2007 May 24.

Abstract

OBJECTIVES

The objective of the study was to investigate the incidence rate of postpartum-onset major depression (PPMD) and to examine associated sociodemographic characteristics, obstetric factors, and personality disorders.

METHOD

The study data were obtained from 302 women who delivered at a child and maternity hospital. We interviewed the new mothers on the first day of their childbirth and at 6 weeks postpartum. Major depression and axis II diagnoses were determined by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, Personality Disorders, respectively.

RESULTS

Nineteen (6.3%) women had new-onset major depression during 6 weeks postpartum. Postpartum-onset major depression was unrelated to age, educational level, employment status, planned or unplanned pregnancy, history of abortion and gestational complications, term of delivery, type of delivery, sex of the baby, and mother's breast-feeding. Frequency of primiparity and of avoidant, dependent, and obsessive-compulsive personality disorders was higher in women with PPMD than that in women without PPMD. As a result of logistic regression analysis, the independent predictor of PPMD was the presence of avoidant, dependent, and obsessive-compulsive personality disorders.

CONCLUSION

Our results suggest that childbearing women with avoidant, dependent, and obsessive-compulsive personality disorders have increased risk of new-onset major depression during the postpartum period.

摘要

目的

本研究的目的是调查产后发作的重度抑郁症(PPMD)的发病率,并检查相关的社会人口学特征、产科因素和人格障碍。

方法

研究数据来自一家妇幼医院的302名分娩妇女。我们在她们分娩第一天和产后6周对这些新妈妈进行了访谈。重度抑郁症和轴II诊断分别通过《精神障碍诊断与统计手册》第四版的结构化临床访谈和《精神障碍诊断与统计手册》修订第三版人格障碍的结构化临床访谈来确定。

结果

19名(6.3%)妇女在产后6周内出现新发重度抑郁症。产后发作的重度抑郁症与年龄、教育水平、就业状况、计划内或计划外怀孕、流产史和妊娠并发症、分娩孕周、分娩方式、婴儿性别以及母亲是否母乳喂养无关。初产频率以及回避型、依赖型和强迫型人格障碍在PPMD妇女中的发生率高于无PPMD的妇女。经过逻辑回归分析,PPMD的独立预测因素是存在回避型、依赖型和强迫型人格障碍。

结论

我们的结果表明,患有回避型、依赖型和强迫型人格障碍的育龄妇女在产后期间新发重度抑郁症的风险增加。

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