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当代一组患者中行原发性腹膜后淋巴结清扫术的短期发病率

Short-term morbidity of primary retroperitoneal lymph node dissection in a contemporary group of patients.

作者信息

Beck Stephen D W, Peterson Matthew D, Bihrle Richard, Donohue John P, Foster Richard S

机构信息

Department of Urology, Indiana University Medical Center, Indianapolis, Indiana 46202, USA.

出版信息

J Urol. 2007 Aug;178(2):504-6; discussion 506. doi: 10.1016/j.juro.2007.03.123. Epub 2007 Jun 11.

Abstract

PURPOSE

We defined the blood loss, operative time and short-term morbidity of primary retroperitoneal lymph node dissection in a contemporary series to assess whether laparoscopic retroperitoneal lymph node dissection actually confers the magnitude of benefit claimed.

MATERIALS AND METHODS

A retrospective chart review was performed of 75 consecutive patients who underwent primary retroperitoneal lymph node dissection during the 18 months ending May 2005. Two patients were excluded, including 1 who underwent right hemicolectomy for cecal adenocarcinoma and 1 with a pure seminomatous intra-abdominal testicle.

RESULTS

Of the 73 patients 69 (94%) underwent unilateral dissection and 60 (82.2%) underwent a nerve sparing procedure. Mean operative time was 132 minutes (range 81 to 246) and mean blood loss was 207 cc (range 50 to 500). Nasogastric tubes were placed in 2 patients (2.7%). Mean time to start clear liquids was 1.0 day. Mean hospital stay was 2.8 days (range 2 to 4).

CONCLUSIONS

The short-term morbidity of open retroperitoneal lymph node dissection, including operative time, blood loss and hospital stay, has significantly improved compared to historical controls. Perioperative management has changed with time. Comparing the morbidity of laparoscopic retroperitoneal lymph node dissection to that of historical controls is inappropriate.

摘要

目的

我们在一个当代系列研究中确定了原发性腹膜后淋巴结清扫术的失血量、手术时间和短期发病率,以评估腹腔镜腹膜后淋巴结清扫术是否真的能带来所宣称的巨大益处。

材料与方法

对在2005年5月结束的18个月期间连续接受原发性腹膜后淋巴结清扫术的75例患者进行回顾性病历审查。排除2例患者,其中1例因盲肠腺癌接受右半结肠切除术,1例为单纯腹腔内睾丸精原细胞瘤患者。

结果

73例患者中,69例(94%)接受了单侧清扫,60例(82.2%)接受了保留神经的手术。平均手术时间为132分钟(范围81至246分钟),平均失血量为207毫升(范围50至500毫升)。2例患者(2.7%)放置了鼻胃管。开始进清流食的平均时间为1.0天。平均住院时间为2.8天(范围2至4天)。

结论

与历史对照相比,开放性腹膜后淋巴结清扫术的短期发病率,包括手术时间、失血量和住院时间,有了显著改善。围手术期管理随时间发生了变化。将腹腔镜腹膜后淋巴结清扫术的发病率与历史对照进行比较是不合适的。

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