Winstock Adam R, Lea Toby, Ritter Alison
Drug Health Services, Sydney South West Area Health Service, Australia.
Drug Alcohol Rev. 2007 Jul;26(4):411-6. doi: 10.1080/09595230701373891.
The introduction of buprenorphine - naloxone in Australia in April 2006 has permitted the revision of takeaway policies in many states and has introduced the possibility of unsupervised treatment. This study explored the implications of the introduction of buprenorphine - naloxone in terms of cost to patients through a survey of pharmacists' intended pricing practices. The aim of the research was to examine the intentions of pharmacists in relation to fees for buprenorphine - naloxone and study the potential implications to patients when compared with the existing fee structure for methadone and for buprenorphine alone.
A self-complete questionnaire was mailed to every community pharmacy in New South Wales (NSW) (n = 593) dispensing methadone or buprenorphine to people with opioid dependence. A response rate of 68.6% (n = 407) was achieved after three mailouts.
The majority of pharmacies charged a flat weekly fee for methadone (92.2%; mean = $31.90) and buprenorphine (74.8%; mean = $31.00). The mean intended fees for buprenorphine - naloxone according to different dosing and takeaway regimens ranged from $19.19 per week for no supervised doses and fortnightly takeaways to a $30.88 per week flat fee. There appeared to be little variation in fee structure irrespective of the takeaway regimen, until reaching the 2 weeks' unsupervised dose regimen.
This study highlights the importance of the early dissemination of unambiguous information regarding the introduction of a new medication, especially where supervised dispensing through community pharmacies is essential to the provision of treatment. The potential impact upon the successful rollout of a new treatment paradigm that was developed to benefit stable patients in the community may be jeopardised when such processes are not followed.
2006年4月丁丙诺啡 - 纳洛酮在澳大利亚投入使用,这使得许多州能够修订外带政策,并引入了无监督治疗的可能性。本研究通过对药剂师预期定价做法的调查,探讨了丁丙诺啡 - 纳洛酮的引入对患者成本的影响。该研究的目的是检查药剂师对丁丙诺啡 - 纳洛酮费用的意图,并与现有的美沙酮和单独丁丙诺啡费用结构相比,研究其对患者的潜在影响。
向新南威尔士州(NSW)(n = 593)中为阿片类药物依赖者配给美沙酮或丁丙诺啡的每家社区药房邮寄一份自填式问卷。经过三次邮寄后,回复率达到68.6%(n = 407)。
大多数药房对美沙酮(92.2%;平均 = 31.90美元)和丁丙诺啡(74.8%;平均 = 31.00美元)收取固定的每周费用。根据不同的给药和外带方案,丁丙诺啡 - 纳洛酮的平均预期费用从无监督剂量且每两周外带一次的每周19.19美元到每周30.88美元的固定费用不等。无论外带方案如何,直到达到2周无监督剂量方案之前,费用结构似乎变化不大。
本研究强调了尽早传播关于新药引入的明确信息的重要性,特别是在通过社区药房进行监督配药对治疗提供至关重要的情况下。当不遵循此类流程时,可能会危及为使社区中病情稳定的患者受益而开发的新治疗模式的成功推广。