患有枕叶阵发性发作的儿童癫痫的单卵双胞胎的神经心理学缺陷

Neuropsychological deficits in monozygotic twins with childhood epilepsy with occipital paroxysms.

作者信息

Gagliano Antonella, Ferlazzo Edoardo, Germanò Eva, Calarese Tiziana, Magazù Angela, Sferro Caterina, Tortorella Gaetano

机构信息

Division of Child Neurology and Psychiatry, University of Messina, Messina, Italy.

出版信息

J Clin Exp Neuropsychol. 2007 Jul;29(5):488-95. doi: 10.1080/13803390600788142.

DOI:10.1080/13803390600788142

PMID:17564914

Abstract

We report a unique pair of monozygotic twins with childhood epilepsy with occipital paroxysms who showed subtle cognitive deficits. The twin with a more severe epileptic disorder showed a more severe impairment of cognitive functioning. We suggest that epileptic focus may act as an element of disturbance in the development of primary functions and may give rise to a neuropsychological impairment proportionate to the severity of the epileptic activity.

摘要

我们报告了一对独特的同卵双胞胎，他们患有伴有枕叶阵发的儿童癫痫，且存在细微的认知缺陷。癫痫病症更严重的那个双胞胎，其认知功能受损也更严重。我们认为癫痫病灶可能是初级功能发育过程中的干扰因素，并且可能导致与癫痫活动严重程度相称的神经心理损害。