Dórea José G
Faculty of Health Sciences, Universidade de Brasília, Brasília, Brazil.
Am J Perinatol. 2007 Aug;24(7):387-400. doi: 10.1055/s-2007-982074. Epub 2007 Jun 12.
Breastfeeding is the best natural protection infants have against morbidity and mortality, and the development of safe and effective vaccines has made it possible to immunize children against infectious disease. Both of these mechanisms for ensuring good health in children may be compromised by contact with mercury (Hg). Maternal exposure to environmental Hg during pregnancy can predispose nursing children to neurodevelopmental disorders. Despite the World Health Organization assurance that thimerosal-preserved vaccines are safe to use in infants, the United States, the European Union, and dozens of other countries have eliminated thimerosal as a vaccine preservative and stopped the immunization of children with such vaccines. Because of the increase in environmental pollution and the need to produce cheap and safe vaccines, there is a need to address the uncertainty of vaccine-ethylmercury risk of toxicity and Hg exposure during breastfeeding.
母乳喂养是婴儿抵御发病和死亡的最佳天然保护方式,而安全有效的疫苗研发使得儿童能够针对传染病进行免疫接种。这两种保障儿童健康的机制都可能因接触汞(Hg)而受到损害。孕期母亲接触环境中的汞会使哺乳的儿童易患神经发育障碍。尽管世界卫生组织保证含硫柳汞的疫苗对婴儿使用是安全的,但美国、欧盟和其他几十个国家已不再使用硫柳汞作为疫苗防腐剂,并停止使用此类疫苗为儿童进行免疫接种。由于环境污染加剧以及生产廉价安全疫苗的需求,有必要解决母乳喂养期间疫苗乙基汞毒性风险和汞暴露的不确定性问题。