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同步:钙昼夜节律振荡的来龙去脉

In SYNC: the ins and outs of circadian oscillations in calcium.

作者信息

Imaizumi Takato, Schroeder Julian I, Kay Steve A

机构信息

Department of Biochemistry, Scripps Research Institute, La Jolla, CA 92037, USA.

出版信息

Sci STKE. 2007 Jun 12;2007(390):pe32. doi: 10.1126/stke.3902007pe32.

Abstract

Many stimuli induce short-term increases in the cytosolic concentration of free calcium ions (Ca(2+)) that encode signaling information about diverse physiological and developmental events. Slow cytosolic Ca(2+) oscillations that span an entire day have also been discovered in both plants and animals; it is thought that these daily Ca(2+) oscillations may encode circadian clock signaling information. A recent study focusing on the characterization of the extracellular Ca(2+)-sensing receptor (CAS) has provided insight into the molecular mechanisms by which the daily Ca(2+) oscillation in plants is generated. We summarize the major findings regarding daily oscillations of cytosolic Ca(2+) concentrations in plants and animals, and discuss hypothetical biological roles for the circadian clock-regulated physiology in plants.

摘要

许多刺激会导致游离钙离子(Ca(2+))的胞质浓度短期升高,这些钙离子编码有关各种生理和发育事件的信号信息。在植物和动物中都发现了持续一整天的缓慢胞质Ca(2+)振荡;据认为,这些每日Ca(2+)振荡可能编码生物钟信号信息。最近一项专注于细胞外Ca(2+)-传感受体(CAS)特性表征的研究,为植物中每日Ca(2+)振荡产生的分子机制提供了见解。我们总结了关于植物和动物中胞质Ca(2+)浓度每日振荡的主要发现,并讨论了生物钟调节的生理学在植物中的假设生物学作用。

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