肺组织胞浆菌病的诊断与治疗：3例报告
[Diagnosis and treatment of pulmonary histoplasmoma: report of 3 cases].
作者信息
Shen Gang, Chai Ying, Zhang Guo-Fei, Wei Hong-Quan, Yue Lan
机构信息
Department of Thoracic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
出版信息
Zhonghua Yi Xue Za Zhi. 2007 Mar 20;87(11):760-2.
OBJECTIVE
To investigate the diagnosis and treatment of pulmonary histoplasmoma.
METHODS
The clinical data of 3 patients with pulmonary histoplasmoma. 2 males, both 49-years-old, and 1 female, 27-years-old, were analyzed.
RESULTS
Nodules in the lung, regardless solitary or multiple, with clear border and calcification, were the first radiological finding. All 3 patients were misdiagnosed as with tuberculosis or primary or metastatic lung neoplasm and underwent operation. The diagnosis was confirmed after surgery. Pathological examination showed caseous necrosis and a great amount of histoplasma in the multinuclear cells. Follow-up lasting 1, 2, and 3 years respectively showed no recurrence.
CONCLUSION
Pulmonary nodule, regardless solitary or multiple, with clear border and calcification, is the first radiological finding of pulmonary histoplasmoma Autopsy is necessary for diagnosis of pulmonary histoplasmoma, difficult to diagnose, however, with a good prognosis.
目的
探讨肺组织胞浆菌病的诊断与治疗。
方法
分析3例肺组织胞浆菌病患者的临床资料。其中男性2例，均为49岁，女性1例，27岁。
结果
肺部结节，无论单发或多发，边界清晰且有钙化，是最初的影像学表现。3例患者均被误诊为肺结核或原发性或转移性肺肿瘤并接受了手术。术后确诊。病理检查显示干酪样坏死，多核细胞内有大量组织胞浆菌。分别随访1年、2年和3年，均无复发。
结论
肺部结节，无论单发或多发，边界清晰且有钙化，是肺组织胞浆菌病最初的影像学表现。肺组织胞浆菌病的诊断需要尸检，然而其诊断困难，但预后良好。
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