Shivaji S, Kumar Vivek, Mitra Kasturi, Jha Kula Nand
Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Soc Reprod Fertil Suppl. 2007;63:295-312.
Capacitation was discovered independently by Austin and Chang in the early 1950s and was defined as the obligate period of residence of spermatozoa in the female reproductive tract, which confers on the spermatozoa the ability to fertilize an oocyte. The molecular basis of the phenomenon of capacitation is poorly understood despite the fact that it is an important event preceding fertilization. This review presents our current understanding of the signalling events involved in the process of capacitation.
获能是20世纪50年代初由奥斯汀和张独立发现的，被定义为精子在雌性生殖道中必须停留的时期，这使精子获得了使卵母细胞受精的能力。尽管获能现象是受精前的一个重要事件，但其分子基础仍知之甚少。本综述介绍了我们目前对获能过程中涉及的信号事件的理解。
