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剖宫产术中子宫切口扩张对围手术期出血的影响:一项前瞻性随机临床试验

[The effect of uterine incision expansion at caesarean delivery on perioperative haemorrhage: a prospective randomised clinical trial].

作者信息

Hidar S, Jerbi M, Hafsa A, Slama A, Bibi M, Khaïri H

机构信息

Service de Gynécologie Obstétrique, Départment de Gynécologie Obstétrique, CHU F. Hached Sousse, Tunisie.

出版信息

Rev Med Liege. 2007 Apr;62(4):235-8.

Abstract

To determine if blunt or sharp expansion of the uterus at caesarean delivery is associated with increased maternal peripartum haemorrhage as estimated by the drop in hematocrit. Prospective randomised intention to treat clinical trial of women undergoing elective or urgent caesarean delivery at at least 36 weeks gestation. Two study groups were formed; after an initial hysterotomy which consisted in a transverse uterine incision of the lower segment, in the blunt group, the surgeon's indexes expanded the initial incision bilaterally and cephalad; in the sharp group, expansion of the initial incision was made using scissors. The primary outcome measure was the mean drop in hematocrit and p < 0.05 was considered significant. Three hundred women were randomised: 153 to the sharp group and 147 to the blunt group. The demographic and clinical characteristics of the two populations were similar. There were no statistically significant differences between the groups in estimated blood loss as assessed by the mean drop in hematocrit (%) (respectively 1.71 +/- 3.18 versus blunt group 1.91 +/- 3.28 p = 0.58 non significant). Our findings support that sharp or blunt expansion of hysterotomy during caesarean section equally affect blood loss as estimated by drop in hematocrit.

摘要

通过血细胞比容下降来评估剖宫产时子宫钝性或锐性扩张是否与产妇围产期出血增加相关。对妊娠至少36周行择期或急诊剖宫产的妇女进行前瞻性随机意向性治疗临床试验。形成两个研究组;在最初的子宫切开术(即下段子宫横切口)后,钝性组中,外科医生的食指从两侧和头侧扩大初始切口;在锐性组中,用剪刀扩大初始切口。主要结局指标是血细胞比容的平均下降幅度,p<0.05被认为具有统计学意义。300名妇女被随机分组:153名进入锐性组,147名进入钝性组。两组人群的人口统计学和临床特征相似。通过血细胞比容平均下降幅度评估的估计失血量在两组之间无统计学显著差异(分别为1.71±3.18与钝性组1.91±3.28,p = 0.58,无显著性)。我们的研究结果支持,剖宫产时子宫切开术的锐性或钝性扩张对血细胞比容下降所估计的失血量影响相同。

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