Haug B A, Holzgraefe M
Department of Neurology, University of Göttingen, FRG.
Eur Neurol. 1991;31(6):423-5. doi: 10.1159/000116708.
A case of essential tremor since early adultness is presented, which has been treated successfully with the acetylcholine precursor 2-dimethylaminoethanol (deanol) for 10 years. Development of a marked dyskinesia syndrome affecting predominantly orofacial and respiratory musculature has been noticed with this medication. Partial remission after discontinuation and a favorable response to anticholinergics are suggestive of an adverse drug effect.
本文报告一例自成年早期起病的特发性震颤患者，使用乙酰胆碱前体2-二甲基氨基乙醇（二甲氨基乙醇）成功治疗10年。使用该药物后，出现了以口面部和呼吸肌为主的明显运动障碍综合征。停药后部分缓解，对抗胆碱能药物反应良好，提示为药物不良反应。
