Tyler T, Rosenbaum H D
AJR Am J Roentgenol. 1976 Jan;126(1):23-31. doi: 10.2214/ajr.126.1.23.
A 59 year old while female with striking carpal and tarsal osteolysis is reported. The process primarily involves the carpals and tarsals but includes other sites. The pertinent literature is reviewed and a simplified classification of idiopathic multicentric osteolysis is presented. Idiopathic multicentric osteolysis may be sporadic but can demonstrate either dominant or recessive inheritance. There may or may not be associated nephropathy. The underlying mechanism appears similar in all variations of this condition. Gorham's disease, the Winchester syndrome, and other osteolytic conditions which may predominantly affect the tarsal and carpal bones most likely are totally different processes, unrelated to idiopathic multicentric osteolysis.
本文报道了一名59岁患有明显腕骨和跗骨骨质溶解症的白人女性。该病症主要累及腕骨和跗骨，但也包括其他部位。本文回顾了相关文献，并提出了特发性多中心骨质溶解症的简化分类。特发性多中心骨质溶解症可能是散发性的，但也可表现为显性或隐性遗传。可能伴有或不伴有肾病。在该病症的所有变体中，其潜在机制似乎相似。戈勒姆病、温彻斯特综合征以及其他可能主要影响跗骨和腕骨的骨质溶解症，很可能是完全不同的病症过程，与特发性多中心骨质溶解症无关。
