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临床共聚焦显微镜的当前应用。

Current applications of clinical confocal microscopy.

作者信息

Dhaliwal Jasmeet S, Kaufman Stephen C, Chiou Auguste Gy

机构信息

Henry Ford Health System: Ophthalmology, Troy, MI, USA.

出版信息

Curr Opin Ophthalmol. 2007 Jul;18(4):300-7. doi: 10.1097/ICU.0b013e3281b11665.

DOI:10.1097/ICU.0b013e3281b11665
PMID:17568206
Abstract

PURPOSE OF REVIEW

Confocal microscopy's role within ophthalmology has been evolving since the introduction of this technology in 1955. The purpose of this review is to describe the confocal microscope and illustrate its recent ophthalmic applications.

RECENT FINDINGS

Numerous investigators have used confocal microscopy to research ophthalmic disease and to find new diagnostic applications. This review will describe the development and uses of this technology. The cornea was the first ophthalmic tissue to be imaged due to its transparency, although, tissues, such as conjunctiva, are now being studied. This article will review normal confocal corneal appearance and discuss a wide range of recent applications that include corneal infections, dystrophies and disease. Furthermore, this article will discuss recent developments in refractive surgery, ocular surgery and various miscellaneous discoveries.

SUMMARY

Confocal microscopy is developing into a powerful research and diagnostic tool in ophthalmology. The future uses of this novel technology will evolve and is increasingly becoming a vital tool in the ophthalmologist's armamentarium.

摘要

综述目的

自1955年共聚焦显微镜技术问世以来,其在眼科领域的作用一直在不断演变。本综述的目的是介绍共聚焦显微镜,并阐述其近期在眼科的应用。

最新研究发现

众多研究人员已使用共聚焦显微镜来研究眼科疾病并探索新的诊断应用。本综述将描述该技术的发展及应用。由于角膜具有透明性,它是首个被成像的眼科组织,不过,如今结膜等组织也在被研究。本文将回顾共聚焦显微镜下正常角膜的表现,并探讨一系列近期应用,包括角膜感染、营养不良及疾病。此外,本文还将讨论屈光手术、眼科手术及各种其他新发现方面的近期进展。

总结

共聚焦显微镜正发展成为眼科领域一种强大的研究和诊断工具。这项新技术的未来用途将会不断演变,且日益成为眼科医生诊疗手段中的重要工具。

相似文献

1
Current applications of clinical confocal microscopy.临床共聚焦显微镜的当前应用。
Curr Opin Ophthalmol. 2007 Jul;18(4):300-7. doi: 10.1097/ICU.0b013e3281b11665.
2
Clinical in vivo confocal microscopy of the human cornea in health and disease.健康和疾病人群角膜的临床活体共聚焦显微镜检查。
Prog Retin Eye Res. 2010 Jan;29(1):30-58. doi: 10.1016/j.preteyeres.2009.11.001. Epub 2009 Nov 26.
3
Confocal microscopy in ophthalmology.眼科中的共聚焦显微镜检查。
Am J Ophthalmol. 2009 Nov;148(5):639-46. doi: 10.1016/j.ajo.2009.06.022. Epub 2009 Aug 11.
4
Confocal microscopy: a report by the American Academy of Ophthalmology.共聚焦显微镜检查:美国眼科学会的一份报告。
Ophthalmology. 2004 Feb;111(2):396-406. doi: 10.1016/j.ophtha.2003.12.002.
5
Clinical corneal confocal microscopy.临床角膜共焦显微镜检查
Surv Ophthalmol. 2006 Sep-Oct;51(5):482-500. doi: 10.1016/j.survophthal.2006.06.010.
6
In vivo confocal microscopy of the ocular surface.眼表的体内共焦显微镜检查
Am J Ophthalmol. 2010 Apr;149(4):689-90; author reply 690. doi: 10.1016/j.ajo.2009.12.032.
7
In vivo confocal microscopy of human corneal nerves in health, in ocular and systemic disease, and following corneal surgery: a review.健康状态下、眼部及全身性疾病时以及角膜手术后人体角膜神经的体内共聚焦显微镜检查:综述
Br J Ophthalmol. 2009 Jul;93(7):853-60. doi: 10.1136/bjo.2008.150615. Epub 2008 Nov 19.
8
Anterior segment applications of in vivo confocal microscopy.体内共聚焦显微镜在前节的应用。
Semin Ophthalmol. 2015 Jul;30(4):243-51. doi: 10.3109/08820538.2013.839817. Epub 2013 Oct 29.
9
In vivo confocal microscopy of the ocular surface: where are we now?
Br J Ophthalmol. 2009 Jul;93(7):850-2. doi: 10.1136/bjo.2008.152678.
10
[Confocal microscopy and the cornea].[共聚焦显微镜与角膜]
J Fr Ophtalmol. 1999 Mar;22(2):262-5.

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Quantitative 3-dimensional corneal imaging in vivo using a modified HRT-RCM confocal microscope.使用改良的 HRT-RCM 共焦显微镜对活体进行定量三维角膜成像。
Cornea. 2013 Apr;32(4):e36-43. doi: 10.1097/ICO.0b013e31825ec44e.
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Remote-controlled scanning and automated confocal microscopy through focusing using a modified HRT rostock corneal module.采用改良 HRT rostock 角膜模块进行遥控扫描和聚焦的自动共聚焦显微镜。
Eye Contact Lens. 2009 Nov;35(6):302-8. doi: 10.1097/ICL.0b013e3181bdc435.