戒烟与降低长期死亡率以及冠状动脉搭桥术后重复干预的需求相关。
Smoking cessation is associated with reduced long-term mortality and the need for repeat interventions after coronary artery bypass grafting.
作者信息
Papathanasiou Athanasios, Milionis Haralampos, Toumpoulis Ioannis, Kalantzi Kallirroi, Katsouras Christos, Pappas Kostas, Michalis Lampros, Goudevenos John
机构信息
Department of Cardiology, University Hospital of Ioannina, Ioannina, Greece.
出版信息
Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):448-50. doi: 10.1097/HJR.0b013e3280403c68.
DESIGN
A prospective study.
METHODS
We estimated the impact of smoking cessation on long-term mortality and the need for a revascularization procedure in 1027 patients undergoing a first-ever coronary artery bypass-grafting.
RESULTS AND DISCUSSION
Of the 640 active smokers, 44.7% continued smoking after CABG ('current smokers'), and 55.3% quit. During a 5310 patient-years follow-up, with never smokers as the reference group, current smokers (but not quitters) experienced a significant increase in total mortality (hazard ratio 2.6, 95% confidence interval 1.0-6.6) mainly owing to increased cardiovascular mortality (hazard ratio 4.8, 95% confidence interval 1.1-21.4), as well as increased need for a repeat revascularization procedure (hazard ratio 1.7, 95% confidence interval 1.0-2.9).
设计
一项前瞻性研究。
方法
我们评估了戒烟对1027例首次接受冠状动脉搭桥手术患者的长期死亡率及血运重建术需求的影响。
结果与讨论
在640名现吸烟者中，44.7%在冠状动脉搭桥术后继续吸烟（“当前吸烟者”），55.3%戒烟。在5310患者年的随访期间，以从不吸烟者作为参照组，当前吸烟者（而非戒烟者）的总死亡率显著增加（风险比2.6，95%置信区间1.0 - 6.6），主要归因于心血管死亡率增加（风险比4.8，95%置信区间1.1 - 21.4），以及再次血运重建术需求增加（风险比1.7，95%置信区间1.0 - 2.9）。
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