Al-Tawfiq Jaffar A, AbuKhamsin Abbas
Division of Internal Medicine Specialty Services, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia.
J Infect. 2007 Sep;55(3):249-53. doi: 10.1016/j.jinf.2007.04.008. Epub 2007 Jun 12.
The objective of this study was to describe the features and presentations of Bordetella pertussis infection at Saudi Aramco Medical Services Organization (SAMSO) in Saudi Arabia.
This is a retrospective analysis of the reported cases of B. pertussis from January 1996 to December 2004.
During the study period, there were a total of 156 confirmed cases of B. pertussis infection. There were 88 males and 68 females, with male to female ratio of 1.3:1. Most (n=81; 52%) of the patients were less than six months of age. A large number (n=71; 45.5%) of patients were reported in 2003; 26.8% (n=19) were between 10-19 years and 22.5% (n=16) were >/=20 years of age. Of all the patients, 65 (42%) patients were hospitalized for a median of five days (range: 2-21 days). Of the total cases, 47 (30%) patients were fully vaccinated (>/=3 doses), 48 (30%) had not received any dose of vaccine, 33 (21%) had received one dose and six (3.8%) had received two doses. The vaccination status was not known for 22 (14%) patients. However, many of the infected infants were too young to have been eligible for vaccine. A total of 81 patients were less than six months of age and of those 58% (n=47) did not receive any doses, 39.5% (n=32) received one dose and 2.5% (n=2) received two doses.
In this sample of cases of whooping cough arising in the highly vaccinated population of Saudi Arabia, the overwhelming majority of cases were infants less than six months of age and older adults.
本研究的目的是描述沙特阿拉伯沙特阿美医疗服务组织（SAMSO）中百日咳博德特氏菌感染的特征和表现。
这是一项对1996年1月至2004年12月期间报告的百日咳博德特氏菌病例进行的回顾性分析。
在研究期间，共有156例确诊的百日咳博德特氏菌感染病例。其中男性88例，女性68例，男女比例为1.3:1。大多数患者（n = 81；52%）年龄小于6个月。2003年报告了大量患者（n = 71；45.5%）；10 - 19岁的患者占26.8%（n = 19），20岁及以上的患者占22.5%（n = 16）。所有患者中，65例（42%）住院，中位住院天数为5天（范围：2 - 21天）。在所有病例中，47例（30%）患者已完全接种疫苗（≥3剂），48例（30%）未接种任何剂量疫苗，33例（21%）接种了1剂，6例（3.8%）接种了2剂。22例（14%）患者的疫苗接种状况未知。然而，许多受感染的婴儿年龄太小，不符合接种疫苗的条件。共有81例患者年龄小于6个月，其中58%（n = 47）未接种任何剂量疫苗，39.5%（n = 32）接种了1剂，2.5%（n = 2）接种了2剂。
在沙特阿拉伯这个高疫苗接种率人群中出现的百日咳病例样本中，绝大多数病例是年龄小于6个月的婴儿和老年人。
