Favaro Angela, Santonastaso Paolo, Monteleone Palmiero, Bellodi Laura, Mauri Mauro, Rotondo Alessandro, Erzegovesi Stefano, Maj Mario
Department of Neurosciences, University of Padova, Padova, Italy.
J Affect Disord. 2008 Jan;105(1-3):285-9. doi: 10.1016/j.jad.2007.05.010. Epub 2007 Jun 12.
Few studies, to date, have investigated the relationship between self-damaging behavior and the presence of comorbid psychiatric diagnoses in eating disorders. The aim of the present study was to investigate the axis I and II comorbidity in subjects with bulimia nervosa who report self-injurious behavior and/or suicide attempt.
The subjects were 95 patients with purging type bulimia nervosa who underwent a clinical evaluation assessing the presence of self-injurious behavior and suicide attempts, comorbidity for axis I and II psychiatric disorders and temperament.
No axis I diagnosis was associated with any type of self-injurious behavior, whereas social phobia and bipolar disorder were linked to attempted suicide. Significant independent predictors of impulsive self-injurious behavior were the presence of childhood sexual abuse, high harm avoidance scores, and high self-transcendence scores, whereas childhood sexual abuse, the presence of a cluster B personality disorder, and a low self-directedness were predictors of suicide attempts. Compulsive self-injurious behavior was significantly associated with harm avoidance and cluster C personality disorders. Harm avoidance was also associated with skin picking.
Personality disorders are a frequent correlate of the presence of SIB in purging bulimia nervosa. However, temperament seems to play a more important role. Further studies on larger samples are necessary to confirm our findings in bulimia nervosa and to extend them to other patient populations.
迄今为止,很少有研究调查饮食失调中自我伤害行为与共病精神疾病诊断之间的关系。本研究的目的是调查报告有自我伤害行为和/或自杀未遂的神经性贪食症患者的轴I和轴II共病情况。
研究对象为95例清除型神经性贪食症患者,他们接受了临床评估,以评估自我伤害行为和自杀未遂的情况、轴I和轴II精神疾病共病情况以及气质类型。
轴I诊断与任何类型的自我伤害行为均无关联,而社交恐惧症和双相情感障碍与自杀未遂有关。冲动性自我伤害行为的显著独立预测因素包括童年期性虐待、高回避伤害得分和高自我超越得分,而童年期性虐待、B类人格障碍的存在以及低自我导向是自杀未遂的预测因素。强迫性自我伤害行为与回避伤害和C类人格障碍显著相关。回避伤害也与抠皮肤行为有关。
人格障碍是清除型神经性贪食症中自我伤害行为存在的常见相关因素。然而,气质似乎发挥着更重要的作用。有必要对更大样本进行进一步研究,以证实我们在神经性贪食症中的发现,并将其扩展到其他患者群体。