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[A hepatocellular carcinoma revealed by paraplegia caused by a vertebral metastasis].[一例因椎体转移导致截瘫而发现的肝细胞癌]
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本文引用的文献

1
Spinal tumors.脊柱肿瘤
Eur J Radiol. 2004 May;50(2):159-76. doi: 10.1016/j.ejrad.2003.10.021.
2
[A case of primary hepatocellular carcinoma with metastasis to the spinal cord].
Taehan Kan Hakhoe Chi. 2002 Jun;8(2):218-22.
3
The diagnosis and treatment of metastatic spinal tumor.转移性脊柱肿瘤的诊断与治疗
Oncologist. 1999;4(6):459-69.
4
Nervous system involvement by metastatic hepatocellular carcinoma.
J Neurooncol. 1998 Jan;36(1):85-90. doi: 10.1023/a:1005716408970.
5
Intradural parenchymal involvement in the spinal subarachnoid space associated with primary lung cancer.原发性肺癌相关的脊髓蛛网膜下腔内硬脊膜内实质受累。
Cancer. 1993 Nov 1;72(9):2583-8. doi: 10.1002/1097-0142(19931101)72:9<2583::aid-cncr2820720912>3.0.co;2-k.
6
Hepatoma presenting as a cerebellar metastasis.以小脑转移瘤形式出现的肝癌。
J Comput Tomogr. 1982 Apr;6(1):65-8. doi: 10.1016/0149-936x(82)90015-7.
7
Intramedullary spinal cord metastases. Clinical and radiographic findings in nine cases.脊髓髓内转移瘤。9例患者的临床及影像学表现
Neurology. 1972 Dec;22(12):1222-31. doi: 10.1212/wnl.22.12.1222.
8
Clinical features and natural history of intramedullary spinal cord metastasis.脊髓髓内转移瘤的临床特征与自然病史
Cancer. 1985 Nov 1;56(9):2305-14. doi: 10.1002/1097-0142(19851101)56:9<2305::aid-cncr2820560928>3.0.co;2-x.
9
Hepatocellular carcinoma with central nervous system metastasis: a case report and literature review.肝细胞癌伴中枢神经系统转移:一例报告及文献综述
Med Pediatr Oncol. 1991;19(2):139-44. doi: 10.1002/mpo.2950190215.

一名因神经学检查发现患有肝细胞癌脊柱转移的患者。

A patient with spinal metastasis from hepatocellular carcinoma discovered from neurological findings.

作者信息

Tamaki Katsuyoshi, Shimizu Ichiro, Urata Mari, Kohno Nao, Fukuno Hiroshi, Ito Susumu, Sano Nobuya

机构信息

Department of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, Tokushima University School of Medicine, Kuramoto-cho, Tokushima 770-8503, Japan.

出版信息

World J Gastroenterol. 2007 May 21;13(19):2758-60. doi: 10.3748/wjg.v13.i19.2758.

DOI:10.3748/wjg.v13.i19.2758
PMID:17569150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4147130/
Abstract

Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of the diseases and time. We report a patient with hepatocellular carcinoma (HCC) who was suspected of having spinal lesions based on neurological findings, and a metastatic spinal tumor was found by imaging examination. Assuming that metastasis had occurred at the time lumbar pain developed, the patient reached the level of gait disturbance within only 4 mo, showing a rapid advancement of symptoms. If early diagnosis had been possible, treatment could be performed before acute myelopathy progressed to complete paralysis. We speculate that the terminal stage of HCC is not only liver failure associated with intrahepatic lesions but also metastasis to other regions, treatment for individual pathologies therefore, will be needed, which constitutes an important issue.

摘要

尽管脊柱肿瘤并不常见,但它们可能会降低生存率或导致四肢严重的功能障碍。恶性肿瘤的脊柱转移瘤可引发脊髓压迫症状,如截瘫、四肢瘫和膀胱直肠功能障碍,这些症状会随着疾病进展和时间而加重。我们报告了一名肝细胞癌(HCC)患者,根据神经学检查结果怀疑其患有脊柱病变,经影像学检查发现了脊柱转移瘤。假设在出现腰痛时就已发生转移,该患者仅在4个月内就发展到步态障碍程度,症状进展迅速。如果能够早期诊断,就可以在急性脊髓病发展为完全瘫痪之前进行治疗。我们推测,HCC的终末期不仅是与肝内病变相关的肝衰竭,还包括转移到其他部位,因此需要针对个体病理情况进行治疗,这是一个重要问题。