Oberholzer C, Nüesch R, Häusermann P
Medizinische Poliklinik, Departement Innere Medizin, Universitätsspital Basel.
Praxis (Bern 1994). 2007 May 23;96(21):865-70. doi: 10.1024/1661-8157.96.21.865.
Chronic urticaria is a disease with numerous aetiologies. In case of blood hypereosinophilia a parasitosis is probable an should be mentioned. Infections with echinococcus and helminths can cause IgE mediated release of histamine. Different cytokines are involved and lead to chronic urticaria as well. There are only a few case repoorts about chronic urticaria caused by amoebiasis. The transmission of amoebas is faeco oral and the pathogen can be detected with stool examinations or with testing of antigens or molecular methods. This case showed a remission of chronic urticaria after treatment of the amboebiasis with metronidazole and paromomycine. Therfore a direct causal connection of the amoebiasis and chronic urticaria can be assumed.
慢性荨麻疹是一种病因众多的疾病。在血液嗜酸性粒细胞增多的情况下,寄生虫病很有可能发生,应予以提及。棘球蚴和蠕虫感染可导致IgE介导的组胺释放。不同的细胞因子也参与其中并导致慢性荨麻疹。关于阿米巴病引起慢性荨麻疹的病例报告很少。阿米巴的传播途径是粪口传播,病原体可通过粪便检查、抗原检测或分子方法检测到。该病例在用甲硝唑和巴龙霉素治疗阿米巴病后,慢性荨麻疹得到缓解。因此,可以认为阿米巴病与慢性荨麻疹之间存在直接因果关系。