薰衣草叶香科科对D（+）-半乳糖胺诱导的大鼠肝损伤的保肝活性。

Hepatoprotective activity of the Leucas lavandulaefolia on D(+)galactosamine-induced hepatic injury in rats.

作者信息

Chandrashekar K S, Prasanna K S, Joshi A B

机构信息

Department of Pharmacognosy, NGSM Institute of Pharmaceutical Sciences, Nanthoor, Mangalore, India.

出版信息

Fitoterapia. 2007 Sep;78(6):440-2. doi: 10.1016/j.fitote.2007.04.010. Epub 2007 May 24.

DOI:10.1016/j.fitote.2007.04.010

PMID:17570614

Abstract

The chloroform extract of Leucas lavandulaefolia at an oral dose of 200 mg/kg and 400 mg/kg exhibited a significant protection on D(+)galactosamine induced liver damage in rats. Silymarin (25 mg/kg), a known hepatoprotective drug used as a standard also exhibited a significant activity.

摘要

薰衣草叶香科科（Leucas lavandulaefolia）的氯仿提取物以200毫克/千克和400毫克/千克的口服剂量对D（+）半乳糖胺诱导的大鼠肝损伤表现出显著的保护作用。水飞蓟素（25毫克/千克），一种用作标准的已知保肝药物，也表现出显著活性。