Yamane Takashi, Maruyama Osamu, Nishida Masahiro, Kosaka Ryo, Sugiyama Daisuke, Miyamoto Yusuke, Kawamura Hiroshi, Kato Takahisa, Sano Takeshi, Okubo Takeshi, Sankai Yoshiyuki, Shigeta Osamu, Tsutsui Tatsuo
Institute of Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, 1-2 Namiki, Tsukuba, 305-8564, Japan.
J Artif Organs. 2007;10(2):71-6. doi: 10.1007/s10047-006-0370-z. Epub 2007 Jun 20.
A noncontact type centrifugal pump without any complicated control or sensing modules has been developed as a long-term implantable artificial heart. Centrifugal pumps with impellers levitated by original hydrodynamic bearings were designed and have been modified through numerical analyses and in vitro tests. The hemolysis level was reduced by changing the pressure distribution around the impeller and subsequently expanding the bearing gap. Thrombus formation in the bearing was examined with in vitro thrombogenesis tests and was reduced by changing the groove shapes to increase the bearing-gap flow to 3% of the external flow. Unnecessary vortices around the vanes were also eliminated by changing the number of vanes from four to six.
一种无需任何复杂控制或传感模块的非接触式离心泵已被开发用作长期可植入式人工心脏。设计了采用原始流体动力轴承悬浮叶轮的离心泵,并通过数值分析和体外测试进行了改进。通过改变叶轮周围的压力分布并随后扩大轴承间隙,降低了溶血水平。通过体外血栓形成试验研究了轴承中的血栓形成情况,并通过改变凹槽形状将轴承间隙流量增加到外部流量的3%来减少血栓形成。通过将叶片数量从四个改为六个,还消除了叶片周围不必要的涡流。