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西罗莫司洗脱支架植入术后感染性右冠状动脉瘤-右心室瘘的成功外科治疗

Successful surgical treatment of an infected right coronary artery aneurysm-to-right ventricle fistula after sirolimus-eluting stent implantation.

作者信息

Kishida Ken, Nakaoka Hajime, Sumitsuji Satoru, Nakatsuji Hideaki, Ihara Madoka, Nojima Yuhei, Shimomura Iichiro, Nagai Yoshiyuki

机构信息

Department of Cardiology, Rinku General Medical Center, Izumisano, Suita.

出版信息

Intern Med. 2007;46(12):865-71. doi: 10.2169/internalmedicine.46.6459. Epub 2007 Jun 15.

Abstract

The development of infected coronary aneurismal fistula following stenting seems exceedingly rare. A sirolimus-eluting stent (SES) was implanted in a 70-year-old male patient for acute coronary syndrome. His fever persisted despite treatment with adapted antibiotics. Coronary angiography and 16-multidetector row computed tomography demonstrated the huge right coronary aneurysm forming a fistula to the right ventricle. The aneurysm was excised by surgical treatment. Histopathological examination of the resected mass revealed leucocyte infiltration at the stent site, which lead to the diagnosis of mycotic aneurysm. SESs may play a potential role in locally blunting the innate response to bacterial agents.

摘要

支架置入术后感染性冠状动脉瘤样瘘的发生似乎极为罕见。一名70岁男性患者因急性冠状动脉综合征植入了西罗莫司洗脱支架(SES)。尽管使用了合适的抗生素治疗,他的发热仍持续不退。冠状动脉造影和16排螺旋计算机断层扫描显示巨大的右冠状动脉瘤形成了与右心室的瘘管。通过手术切除了动脉瘤。对切除肿物的组织病理学检查显示支架部位有白细胞浸润,这导致了霉菌性动脉瘤的诊断。SES可能在局部减弱对细菌病原体的固有反应中发挥潜在作用。

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