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Bendamustine and cloretazine: alkylators with sharply contrasting activity in AML.

作者信息

Giles Francis J

机构信息

Division of Hematology and Medical Oncology, San Antonio, TX 78229, USA.

出版信息

Leuk Lymphoma. 2007 Jun;48(6):1064-6. doi: 10.1080/10428190701332464.

DOI:10.1080/10428190701332464
PMID:17577766
Abstract
摘要

相似文献

1
Bendamustine and cloretazine: alkylators with sharply contrasting activity in AML.
Leuk Lymphoma. 2007 Jun;48(6):1064-6. doi: 10.1080/10428190701332464.
2
Cloretazine for the treatment of acute myeloid leukemia.氯雷他嗪用于治疗急性髓系白血病。
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Cloretazine (VNP40101M), a novel sulfonylhydrazine alkylating agent, in patients age 60 years or older with previously untreated acute myeloid leukemia.氯雷他嗪(VNP40101M),一种新型的磺酰肼烷基化剂,用于60岁及以上先前未经治疗的急性髓性白血病患者。
J Clin Oncol. 2007 Jan 1;25(1):25-31. doi: 10.1200/JCO.2006.07.0961. Epub 2006 Dec 4.
4
A pilot study of bendamustine in elderly patients with high-risk MDS and AML.苯达莫司汀用于高危骨髓增生异常综合征和急性髓细胞白血病老年患者的一项试点研究。
Leuk Lymphoma. 2007 Jun;48(6):1161-6. doi: 10.1080/10428190701332449.
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Bendamustine in CLL: How quickly will today's consensus become tomorrow's memory?苯达莫司汀治疗慢性淋巴细胞白血病:如今的共识会多快成为明日的记忆?
Leuk Res. 2014 Nov;38(11):1267-8. doi: 10.1016/j.leukres.2014.08.003. Epub 2014 Aug 11.
6
Bendamustine: a bridge to longer term solutions in heavily treated Hodgkin lymphoma.
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Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models.氯雷他嗪(VNP40101M)单独及与氟达拉滨联合应用于小鼠肿瘤和人异种移植肿瘤模型中的抗肿瘤疗效。
Cancer Chemother Pharmacol. 2007 Jun;60(1):45-51. doi: 10.1007/s00280-006-0345-z. Epub 2007 Jan 26.
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[Mechanisms of action and clinical effectiveness of the newly approved anti-cancer drug bendamustine].[新批准的抗癌药物苯达莫司汀的作用机制及临床疗效]
Nihon Yakurigaku Zasshi. 2011 Jul;138(1):26-32. doi: 10.1254/fpj.138.26.
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Bendamustine and stem-cell mobilization: not so bad!
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Preclinical evaluation of Laromustine for use in combination with radiation therapy in the treatment of solid tumors.拉罗曲塞联合放疗治疗实体瘤的临床前评估。
Int J Radiat Biol. 2012 Mar;88(3):277-85. doi: 10.3109/09553002.2012.638359. Epub 2011 Dec 20.
2
Quantitative relationship between guanine O(6)-alkyl lesions produced by Onrigin™ and tumor resistance by O(6)-alkylguanine-DNA alkyltransferase.O(6)- 烷化鸟嘌呤-DNA 烷基转移酶对 Onrigin™ 产生的鸟嘌呤 O(6)- 烷化损伤与肿瘤耐药性的定量关系。
Biochem Pharmacol. 2010 Nov 1;80(9):1317-25. doi: 10.1016/j.bcp.2010.07.022. Epub 2010 Jul 21.
3
Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine.
抗癌前药氯雷他嗪对人DNA聚合酶β活性的抑制作用。
Biochem Biophys Res Commun. 2009 Jan 16;378(3):419-23. doi: 10.1016/j.bbrc.2008.11.042. Epub 2008 Nov 21.