Benito-León Julián, Arpa Javier, Louis Elan D, Herrera Inmaculada, De La Loma Asia
Department of Neurology, Móstoles General Hospital, Móstoles, Madrid, Spain.
Scand J Infect Dis. 2007;39(6-7):623-5. doi: 10.1080/00365540601115953.
Isolated CNS Whipple disease (WD) carries a poor prognosis, particularly if untreated. We describe 2 patients with isolated CNS WD who presented unusually with an acute onset followed by a relapsing-remitting course. Neither was diagnosed with WD until they had had several relapses.
孤立性中枢神经系统惠普尔病（WD）预后较差，尤其是未经治疗时。我们描述了2例孤立性中枢神经系统WD患者，他们起病异常急骤，随后呈复发-缓解病程。两人在多次复发后才被诊断为WD。
