Boiten J, Lodder J
Department of Neurology, University Hospital Maastricht, The Netherlands.
J Neurol Sci. 1991 Oct;105(2):150-4. doi: 10.1016/0022-510x(91)90138-w.
In 50 patients with computed tomography-verified small, deep, lacunar, infarcts from a prospective stroke registry, we studied the lesion site in relationship with the clinical syndromes pure motor stroke, sensorimotor stroke and ataxic hemiparesis. Seventy per cent (95% confidence interval: 57-83%) of the lesions were located in the posterior limb of the internal capsule or adjacent paraventricular region, affecting the corticospinal tract in pure motor stroke, as well as the thalamocortical tract in sensorimotor stroke, and the cerebellar (dentato(rubro)thalamocortical and corticopontocerebellar) pathways in ataxic hemiparesis. This most frequently involved area is supplied by the anterior choroidal artery, indicating that this artery is the predominant deep, penetrating artery involved in small vessel disease causing lacunar stroke syndromes.
在一项前瞻性卒中登记研究中，我们对50例经计算机断层扫描证实为小的、深部的、腔隙性梗死的患者进行了研究，探讨了病变部位与纯运动性卒中、感觉运动性卒中和共济失调性偏瘫等临床综合征之间的关系。70%（95%置信区间：57 - 83%）的病变位于内囊后肢或邻近的脑室旁区域，在纯运动性卒中中影响皮质脊髓束，在感觉运动性卒中中影响丘脑皮质束，在共济失调性偏瘫中影响小脑（齿状核（红核）丘脑皮质和皮质脑桥小脑）通路。这个最常受累的区域由脉络膜前动脉供血，表明该动脉是导致腔隙性卒中综合征的小血管疾病中主要的深部穿通动脉。
