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经细针穿刺细胞学诊断的原发性乳腺单纯鳞状细胞癌:一项使用液基细胞学的病例研究

Primary pure squamous cell carcinoma of the breast diagnosed by fine-needle aspiration cytology: a case study using liquid-based cytology.

作者信息

Vera-Alvarez J, García-Prats M D, Marigil-Gómez M, Abascal-Agorreta M, López-López J I, Ramón-Cajal J M

机构信息

Department of Pathology, San Jorge Hospital, Huesca, Spain.

出版信息

Diagn Cytopathol. 2007 Jul;35(7):429-32. doi: 10.1002/dc.20658.

DOI:10.1002/dc.20658
PMID:17580346
Abstract

Pure primary squamous cell carcinoma (SCC) is an extremely rare type of breast tumor. We report one of such cases in a 32-year-old woman, diagnosed by fine-needle aspiration cytology (FNAC). Aspiration smears were characterized by squamous cells, both isolated and in aggregates, at various stages of maturation. The tumor was excised, and the histologic sections confirmed the cytologic diagnosis. Pure primary SCC of the breast has a distinctive cytomorphologic appearance, and diagnosis of this tumor by FNAC is possible. For its diagnosis, the exclusion of SCC of local cutaneous structures and metastasis of distant squamous carcinoma are mandatory.

摘要

纯原发性鳞状细胞癌(SCC)是一种极其罕见的乳腺肿瘤类型。我们报告了一名32岁女性的此类病例,通过细针穿刺细胞学检查(FNAC)确诊。穿刺涂片的特征是可见不同成熟阶段的鳞状细胞,既有单个的,也有聚集的。肿瘤被切除,组织学切片证实了细胞学诊断。乳腺纯原发性SCC具有独特的细胞形态学表现,通过FNAC诊断这种肿瘤是可行的。对于其诊断,必须排除局部皮肤结构的SCC和远处鳞状细胞癌的转移。

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