[人类白细胞抗原-B27基因：多态性、进化、分布及其与脊柱关节病的关联]
[Hla-B27 gene: polymorphism, evolution, distribution, and association with spondyloartopathies].
作者信息
Grubić Zorana
机构信息
Klinika za urologiju, Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb.
出版信息
Reumatizam. 2006;53(1):5-10.
PMID:17580542
Abstract
The association between HLA-B27 and ankylosing spondylitis is well established more than thirty years. In spite of numerous studies in this field, a lot of unknown is still present. In this review, polymorphism, evolution, distribution and current pathogenetic hypotheses are presented.
摘要
HLA - B27与强直性脊柱炎之间的关联已得到三十多年的确证。尽管该领域有大量研究，但仍存在许多未知之处。本综述介绍了其多态性、进化、分布及当前的发病机制假说。
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